Based on recent experimental evidence, it appears that it is transitions in bonding between water molecules in liquid and cubic ice states, as shown on the left, which take place on lipid and poly-ionic surfaces, that assist in directing the formation of proteins and nucleic acids into orderly functional structures. Although linear hydration structuring lasts only about a million millionth of a second and is not on surfaces long enough to establish thermodynamic equilibria, it is there long enough to regulate motions and interactions. The articles which follow provide an overview of how the spatial structures of natural molecules, by mimicking the order/disorder properties of environmental water, provide the integral coordination required to produce life.
